FP023ADAPTATION TO POTASSIUM LOADING IN CULTURED ALDOSTERONE SECRETING CELLS
نویسندگان
چکیده
منابع مشابه
Aldosterone-secreting adrenocortical adenoma in children
Aldosterone-secreting adrenocortical adenoma is an unusual cause of secondary hypertension in childhood. We describe an eight year-old female child who presented clinically with weakness of lower limbs, headache and hypertension. Thorough clinical, laboratory and radiological evaluations confirmed the diagnosis of hyperaldosteronism due to a left adrenocortical adenoma. Left adrenalectomy after...
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A case of retroperitoneal leiomyosarcoma (LMS) in a 38-year-old woman who had a tumor in the retroperitoneum with severe hypertension and hypokalemia is presented. Further investigation revealed an elevated serum aldosterone and norepinephrine level. After tumorectomy, the levels of serum aldosterone and norepinephrine successfully normalized; hypertension and hypokalemia were also cured. The t...
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INTRODUCTION Adrenocortical carcinoma is a rare malignancy with a poor prognosis and presents with mass effects and less often with signs of hormone excess (approximately 60% of all adrenocortical carcinoma's). Hormonally active adrenocortical carcinomas most commonly secrete cortisol while the co-secretion of multiple steroid hormones is rare. CASE PRESENTATION We report the case of a 59 yea...
متن کاملProtein kinase C and the modulation of ATP-sensitive potassium channels in insulin-secreting cells.
The Department of Biomedical Science, The University, Western Bank, Sheffield. S10 2TN. patches. However, when exactly the same protocol was carried out cn patches of membrane excised from cells pre-treated overnight with 1 M PMA, pdymyxin-B induced Mock was readily reversible (n=8). There is therefore a marked difference in the mechanism of action of polymyxin B on K+AW channels in the presenc...
متن کاملEffects of 5-hydroxydecanoate on ATP-regulated potassium ion channels in insulin secreting cells.
5-hydmxydecanoate (5-HD) is a component of hydmxyl fatty acids found in milk. Interest in 5-HD has recently been stimulated by the finding that the compound may in fact act as a novel antiarrhythmic agent, because of its blocking actions on ATP-regulated potassium ( K + A ~ ) channels in cardiac myocytes [l]. K+ATP channels play an imponant role in governing the membrane potential of the insuli...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2018
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/gfy104.fp023